Could the dengue virus mutate and find a way to be spread that gets around your mosquitoes?

The dengue ‘virus’ is actually four viruses (or sub types) and a fifth has been identified in Malaysia. They are all transmitted by this species of mosquito. It is clear the virus will mutate – but if you can reduce the mosquito population below the level where it can transmit the disease on an epidemic level you can prevent outbreaks.

Our system works by reducing the number of mosquitoes rather than by blocking the virus in the mosquito. If it did block the virus, you might expect the virus to find a way around that ‘block’. Instead we focus on reducing the sheer numbers of the mosquitoes to trace levels. In effect this is the same strategy people try today (with insecticides) with the exception that our approach has been proven as far more effective in field trials in different countries.